Dozmorov, Mikhail G
Elevated AKR1C3 expression promotes prostate cancer cell survival and prostate cell-mediated endothelial cell tube formation: implications for prostate cancer progression. [electronic resource]
- BMC cancer Dec 2010
- 672 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
ISSN: 1471-2407
Standard No.: 10.1186/1471-2407-10-672 doi
Subjects--Topical Terms: 3-Hydroxysteroid Dehydrogenases--genetics Blotting, Western Cell Line, Tumor Cell Survival Computational Biology Dihydrotestosterone--metabolism Disease Progression Endothelial Cells--drug effects Enzyme-Linked Immunosorbent Assay Estradiol--metabolism Gene Expression Profiling--methods Gene Expression Regulation, Neoplastic Gene Regulatory Networks Humans Hydroxyprostaglandin Dehydrogenases--genetics Insulin-Like Growth Factor I--metabolism Male Neovascularization, Pathologic--enzymology Oligonucleotide Array Sequence Analysis Promoter Regions, Genetic Prostatic Neoplasms--blood supply Protein Kinase Inhibitors--pharmacology Proto-Oncogene Proteins c-akt--antagonists & inhibitors Receptor, IGF Type 1--antagonists & inhibitors Receptors, Calcitriol--metabolism Retinoid X Receptors--metabolism Reverse Transcriptase Polymerase Chain Reaction Signal Transduction Transfection Tumor Suppressor Protein p53--metabolism Up-Regulation Vascular Endothelial Growth Factor A--metabolism