Dozmorov, Mikhail G

Elevated AKR1C3 expression promotes prostate cancer cell survival and prostate cell-mediated endothelial cell tube formation: implications for prostate cancer progression. [electronic resource] - BMC cancer Dec 2010 - 672 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

1471-2407

10.1186/1471-2407-10-672 doi


3-Hydroxysteroid Dehydrogenases--genetics
Blotting, Western
Cell Line, Tumor
Cell Survival
Computational Biology
Dihydrotestosterone--metabolism
Disease Progression
Endothelial Cells--drug effects
Enzyme-Linked Immunosorbent Assay
Estradiol--metabolism
Gene Expression Profiling--methods
Gene Expression Regulation, Neoplastic
Gene Regulatory Networks
Humans
Hydroxyprostaglandin Dehydrogenases--genetics
Insulin-Like Growth Factor I--metabolism
Male
Neovascularization, Pathologic--enzymology
Oligonucleotide Array Sequence Analysis
Promoter Regions, Genetic
Prostatic Neoplasms--blood supply
Protein Kinase Inhibitors--pharmacology
Proto-Oncogene Proteins c-akt--antagonists & inhibitors
Receptor, IGF Type 1--antagonists & inhibitors
Receptors, Calcitriol--metabolism
Retinoid X Receptors--metabolism
Reverse Transcriptase Polymerase Chain Reaction
Signal Transduction
Transfection
Tumor Suppressor Protein p53--metabolism
Up-Regulation
Vascular Endothelial Growth Factor A--metabolism