TY - GEN AU - Takato,Hazuki AU - Yasui,Masahide AU - Ichikawa,Yukari AU - Waseda,Yuko AU - Inuzuka,Kanako AU - Nishizawa,Yoriko AU - Tagami,Atsuro AU - Fujimura,Masaki AU - Nakao,Shinji TI - The specific chymase inhibitor TY-51469 suppresses the accumulation of neutrophils in the lung and reduces silica-induced pulmonary fibrosis in mice SN - 1521-0499 PY - 2011///0609 KW - Animals KW - Bronchoalveolar Lavage Fluid KW - chemistry KW - Chemokine CCL2 KW - metabolism KW - Chemokines, CC KW - Chymases KW - antagonists & inhibitors KW - Cytokines KW - Hydroxyproline KW - Macrophage Inflammatory Proteins KW - Male KW - Mast Cells KW - drug effects KW - Mice KW - Mice, Inbred ICR KW - Neutrophils KW - Pulmonary Fibrosis KW - chemically induced KW - Serine Endopeptidases KW - biosynthesis KW - Silicon Dioxide KW - Sulfonamides KW - pharmacology KW - Thiophenes KW - Transforming Growth Factor beta1 N1 - Publication Type: Journal Article UR - https://doi.org/10.3109/01902148.2010.520815 ER -