TY  - GEN
AU  - Ghosal,Anima
AU  - Yuan,Yuan
AU  - Tong,Wei
AU  - Su,Ai-Duen
AU  - Gu,Chunyan
AU  - Chowdhury,Swapan K
AU  - Kishnani,Narendra S
AU  - Alton,Kevin B
TI  - Characterization of human liver enzymes involved in the biotransformation of boceprevir, a hepatitis C virus protease inhibitor
SN  - 1521-009X
PY  - 2011///0614
KW  - 3-Hydroxysteroid Dehydrogenases
KW  - antagonists & inhibitors
KW  - Aldo-Keto Reductase Family 1 Member C3
KW  - Biotransformation
KW  - drug effects
KW  - Cytochrome P-450 CYP3A
KW  - genetics
KW  - Cytochrome P-450 CYP3A Inhibitors
KW  - Drugs, Investigational
KW  - chemistry
KW  - Enzyme Inhibitors
KW  - pharmacology
KW  - Hepacivirus
KW  - enzymology
KW  - Humans
KW  - Hydroxyprostaglandin Dehydrogenases
KW  - Hydroxysteroid Dehydrogenases
KW  - Kinetics
KW  - Liver
KW  - Molecular Structure
KW  - Oligopeptides
KW  - Oxidation-Reduction
KW  - Proline
KW  - analogs & derivatives
KW  - Recombinant Proteins
KW  - metabolism
KW  - Serine Proteinase Inhibitors
KW  - Stereoisomerism
KW  - Subcellular Fractions
KW  - Urea
KW  - Viral Nonstructural Proteins
N1  - Publication Type: Comparative Study; Journal Article
UR  - https://doi.org/10.1124/dmd.110.036996
ER  -