Ghosal, Anima <br/><br/>
Characterization of human liver enzymes involved in the biotransformation of boceprevir, a hepatitis C virus protease inhibitor.  [electronic resource] 

 -  Drug metabolism and disposition: the biological fate of chemicals  Mar 2011 
 - 510-21 p.  digital 
<br/><br/> Publication Type: Comparative Study; Journal Article 
<br/><br/><label>ISSN: </label>1521-009X 
<br/><br/><label>Standard No.: </label>10.1124/dmd.110.036996  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>3-Hydroxysteroid Dehydrogenases--antagonists & inhibitors<br/>Aldo-Keto Reductase Family 1 Member C3<br/>Biotransformation--drug effects<br/>Cytochrome P-450 CYP3A--genetics<br/>Cytochrome P-450 CYP3A Inhibitors<br/>Drugs, Investigational--chemistry<br/>Enzyme Inhibitors--pharmacology<br/>Hepacivirus--enzymology<br/>Humans<br/>Hydroxyprostaglandin Dehydrogenases--antagonists & inhibitors<br/>Hydroxysteroid Dehydrogenases--antagonists & inhibitors<br/>Kinetics<br/>Liver--enzymology<br/>Molecular Structure<br/>Oligopeptides--chemistry<br/>Oxidation-Reduction<br/>Proline--analogs & derivatives<br/>Recombinant Proteins--metabolism<br/>Serine Proteinase Inhibitors--chemistry<br/>Stereoisomerism<br/>Subcellular Fractions--drug effects<br/>Urea--analogs & derivatives<br/>Viral Nonstructural Proteins--antagonists & inhibitors