TY - GEN AU - Ma,Shuguang AU - Li,Zhiling AU - Lee,Keun-Joong AU - Chowdhury,Swapan K TI - Determination of exposure multiples of human metabolites for MIST assessment in preclinical safety species without using reference standards or radiolabeled compounds SN - 1520-5010 PY - 2012///0320 KW - Animals KW - Area Under Curve KW - Chromatography, High Pressure Liquid KW - standards KW - Humans KW - Isotope Labeling KW - Nitriles KW - blood KW - Pharmaceutical Preparations KW - Piperazines KW - Rabbits KW - Reference Standards KW - Tandem Mass Spectrometry KW - Toxicity Tests KW - Urea KW - analogs & derivatives N1 - Publication Type: Journal Article UR - https://doi.org/10.1021/tx100363k ER -