Ma, Shuguang

Determination of exposure multiples of human metabolites for MIST assessment in preclinical safety species without using reference standards or radiolabeled compounds. [electronic resource] - Chemical research in toxicology Dec 2010 - 1871-3 p. digital

Publication Type: Journal Article

1520-5010

10.1021/tx100363k doi


Animals
Area Under Curve
Chromatography, High Pressure Liquid--standards
Humans
Isotope Labeling
Nitriles--blood
Pharmaceutical Preparations--blood
Piperazines--blood
Rabbits
Reference Standards
Tandem Mass Spectrometry--standards
Toxicity Tests
Urea--analogs & derivatives