TY - GEN AU - Bajaj,Madhu S AU - Ogueli,Godwin I AU - Kumar,Yogesh AU - Vadivel,Kanagasabai AU - Lawson,Gregory AU - Shanker,Sreejesh AU - Schmidt,Amy E AU - Bajaj,S Paul TI - Engineering kunitz domain 1 (KD1) of human tissue factor pathway inhibitor-2 to selectively inhibit fibrinolysis: properties of KD1-L17R variant SN - 1083-351X PY - 2011///0324 KW - Amino Acid Substitution KW - Animals KW - Antifibrinolytic Agents KW - chemistry KW - Aprotinin KW - Blood Coagulation Factors KW - Disease Models, Animal KW - Escherichia coli KW - Fibrinolysis KW - drug effects KW - Glycoproteins KW - Hemorrhage KW - drug therapy KW - Humans KW - Mice KW - Mutation, Missense KW - Protein Folding KW - Protein Structure, Tertiary KW - Recombinant Proteins KW - Structure-Activity Relationship KW - Tranexamic Acid N1 - Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural UR - https://doi.org/10.1074/jbc.M110.191163 ER -