TY - GEN AU - de Jong,E AU - Doedée,A M C M AU - Reis-Fernandes,M A AU - Nau,H AU - Piersma,A H TI - Potency ranking of valproic acid analogues as to inhibition of cardiac differentiation of embryonic stem cells in comparison to their in vivo embryotoxicity SN - 1873-1708 PY - 2011///0920 KW - Abnormalities, Drug-Induced KW - etiology KW - Animal Testing Alternatives KW - Animals KW - Cell Differentiation KW - drug effects KW - Cell Line KW - Cell Survival KW - Dose-Response Relationship, Drug KW - Embryo, Mammalian KW - Embryonic Stem Cells KW - Gene Expression Regulation, Developmental KW - Immunohistochemistry KW - Mice KW - Molecular Structure KW - Myocardial Contraction KW - Myocytes, Cardiac KW - Neural Tube Defects KW - chemically induced KW - Reverse Transcriptase Polymerase Chain Reaction KW - Risk Assessment KW - Structure-Activity Relationship KW - Time Factors KW - Toxicity Tests KW - Valproic Acid KW - analogs & derivatives N1 - Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Review UR - https://doi.org/10.1016/j.reprotox.2010.11.012 ER -