de Jong, E
Potency ranking of valproic acid analogues as to inhibition of cardiac differentiation of embryonic stem cells in comparison to their in vivo embryotoxicity. [electronic resource]
- Reproductive toxicology (Elmsford, N.Y.) May 2011
- 375-82 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Review
ISSN: 1873-1708
Standard No.: 10.1016/j.reprotox.2010.11.012 doi
Subjects--Topical Terms: Abnormalities, Drug-Induced--etiology Animal Testing Alternatives Animals Cell Differentiation--drug effects Cell Line Cell Survival--drug effects Dose-Response Relationship, Drug Embryo, Mammalian--drug effects Embryonic Stem Cells--drug effects Gene Expression Regulation, Developmental--drug effects Immunohistochemistry Mice Molecular Structure Myocardial Contraction--drug effects Myocytes, Cardiac--drug effects Neural Tube Defects--chemically induced Reverse Transcriptase Polymerase Chain Reaction Risk Assessment Structure-Activity Relationship Time Factors Toxicity Tests Valproic Acid--analogs & derivatives