TY - GEN AU - O'Malley,Dervla AU - Liston,Martin AU - Hyland,Niall P AU - Dinan,Timothy G AU - Cryan,John F TI - Colonic soluble mediators from the maternal separation model of irritable bowel syndrome activate submucosal neurons via an interleukin-6-dependent mechanism SN - 1522-1547 PY - 2011///0315 KW - Acetylcholine KW - metabolism KW - Animals KW - Cholinergic Agonists KW - Colon KW - innervation KW - Female KW - Ganglia KW - physiopathology KW - In Vitro Techniques KW - Interleukin-1beta KW - pharmacology KW - Interleukin-6 KW - blood KW - Interleukin-8 KW - Irritable Bowel Syndrome KW - etiology KW - Male KW - Maternal Deprivation KW - Mitogen-Activated Protein Kinases KW - NF-kappa B KW - Neurons KW - drug effects KW - Rats KW - Rats, Sprague-Dawley KW - Receptors, Interleukin-6 KW - Recombinant Proteins KW - STAT3 Transcription Factor KW - Signal Transduction KW - Submucous Plexus KW - Tumor Necrosis Factor-alpha N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1152/ajpgi.00385.2010 ER -