Serum matrilysin correlates with poor survival independently of KRAS and BRAF status in refractory advanced colorectal cancer patients treated with irinotecan plus cetuximab. [electronic resource]
- Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine Apr 2011
- 417-24 p. digital
Publication Type: Journal Article
1423-0380
10.1007/s13277-010-0136-3 doi
Adenocarcinoma--blood Adult Aged Aged, 80 and over Antibodies, Monoclonal--therapeutic use Antibodies, Monoclonal, Humanized Antineoplastic Agents--therapeutic use Biomarkers, Tumor--blood Camptothecin--analogs & derivatives Cetuximab Colorectal Neoplasms--blood Drug Resistance, Neoplasm Drug Therapy, Combination Female Humans Irinotecan Male Matrix Metalloproteinase 7--blood Middle Aged Mutation--genetics Predictive Value of Tests Prognosis Proto-Oncogene Proteins--genetics Proto-Oncogene Proteins B-raf--genetics Proto-Oncogene Proteins p21(ras) Retrospective Studies Survival Rate Treatment Outcome ras Proteins--genetics