Thompson, Michael D
Pegylated interferon alpha targets Wnt signaling by inducing nuclear export of β-catenin. [electronic resource]
- Journal of hepatology Mar 2011
- 506-12 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
ISSN: 1600-0641
Standard No.: 10.1016/j.jhep.2010.07.020 doi
Subjects--Topical Terms: Active Transport, Cell Nucleus--drug effects Animals Antiviral Agents--pharmacology Carcinoma, Hepatocellular--drug therapy Cell Line, Tumor Gene Knockdown Techniques Hep G2 Cells Hepatitis C, Chronic--complications Humans Intercellular Signaling Peptides and Proteins--genetics Interferon alpha-2 Interferon-alpha--pharmacology Liver--drug effects Liver Neoplasms--drug therapy Mice Mice, Transgenic Mutant Proteins--genetics Nuclear Proteins--antagonists & inhibitors Nucleocytoplasmic Transport Proteins--antagonists & inhibitors Polyethylene Glycols--pharmacology RNA, Small Interfering--genetics Recombinant Proteins--genetics Signal Transduction--drug effects Transcription, Genetic--drug effects Wnt Proteins--metabolism beta Catenin--genetics