Thompson, Michael D

Pegylated interferon alpha targets Wnt signaling by inducing nuclear export of β-catenin. [electronic resource] - Journal of hepatology Mar 2011 - 506-12 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1600-0641

10.1016/j.jhep.2010.07.020 doi


Active Transport, Cell Nucleus--drug effects
Animals
Antiviral Agents--pharmacology
Carcinoma, Hepatocellular--drug therapy
Cell Line, Tumor
Gene Knockdown Techniques
Hep G2 Cells
Hepatitis C, Chronic--complications
Humans
Intercellular Signaling Peptides and Proteins--genetics
Interferon alpha-2
Interferon-alpha--pharmacology
Liver--drug effects
Liver Neoplasms--drug therapy
Mice
Mice, Transgenic
Mutant Proteins--genetics
Nuclear Proteins--antagonists & inhibitors
Nucleocytoplasmic Transport Proteins--antagonists & inhibitors
Polyethylene Glycols--pharmacology
RNA, Small Interfering--genetics
Recombinant Proteins--genetics
Signal Transduction--drug effects
Transcription, Genetic--drug effects
Wnt Proteins--metabolism
beta Catenin--genetics