TY - GEN AU - Shen,Ching-Hui AU - Tsai,Ru-Yin AU - Shih,Meng-Shen AU - Lin,Shinn-Long AU - Tai,Yueh-Hwa AU - Chien,Chih-Cheng AU - Wong,Chih-Shung TI - Etanercept restores the antinociceptive effect of morphine and suppresses spinal neuroinflammation in morphine-tolerant rats SN - 1526-7598 PY - 2011///0228 KW - Analgesics, Opioid KW - administration & dosage KW - Animals KW - Anti-Inflammatory Agents KW - Behavior, Animal KW - Drug Tolerance KW - Etanercept KW - Gene Expression Regulation KW - Immunoglobulin G KW - Immunohistochemistry KW - Inflammation KW - chemically induced KW - Inflammation Mediators KW - antagonists & inhibitors KW - Infusion Pumps KW - Infusions, Parenteral KW - Injections, Spinal KW - Interleukin-1beta KW - genetics KW - Interleukin-6 KW - Male KW - Microglia KW - drug effects KW - Morphine KW - Pain Threshold KW - RNA, Messenger KW - metabolism KW - Rats KW - Rats, Wistar KW - Reaction Time KW - Receptors, Tumor Necrosis Factor KW - Reverse Transcriptase Polymerase Chain Reaction KW - Spinal Cord KW - Time Factors KW - Tumor Necrosis Factor-alpha N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1213/ANE.0b013e3182025b15 ER -