TY - GEN AU - Reddy,P Ganapati AU - Bao,Donghui AU - Chang,Wonsuk AU - Chun,Byoung-Kwon AU - Du,Jinfa AU - Nagarathnam,Dhanapalan AU - Rachakonda,Suguna AU - Ross,Bruce S AU - Zhang,Hai-Ren AU - Bansal,Shalini AU - Espiritu,Christine L AU - Keilman,Meg AU - Lam,Angela M AU - Niu,Congrong AU - Steuer,Holly Micolochick AU - Furman,Phillip A AU - Otto,Michael J AU - Sofia,Michael J TI - 2'-deoxy-2'-α-fluoro-2'-β-C-methyl 3',5'-cyclic phosphate nucleotide prodrug analogs as inhibitors of HCV NS5B polymerase: discovery of PSI-352938 SN - 1464-3405 PY - 2011///0314 KW - Administration, Oral KW - Animals KW - Antiviral Agents KW - chemistry KW - Cell Line, Tumor KW - Crystallography, X-Ray KW - Cyclic P-Oxides KW - Enzyme Inhibitors KW - Hepacivirus KW - enzymology KW - Humans KW - Molecular Conformation KW - Nucleosides KW - Nucleotides, Cyclic KW - chemical synthesis KW - Prodrugs KW - Rats KW - Structure-Activity Relationship KW - Viral Nonstructural Proteins KW - antagonists & inhibitors N1 - Publication Type: Journal Article UR - https://doi.org/10.1016/j.bmcl.2010.10.035 ER -