TY - GEN AU - Na,Young-Soon AU - Jung,Kyung-Ah AU - Kim,Seung-Mi AU - Hong,Yong Sang AU - Ryu,Min-Hee AU - Jang,Se Jin AU - Moon,Dae Hyuk AU - Cho,Dong-Hyung AU - Kim,Jin Cheon AU - Lee,Jung Shin AU - Kim,Tae Won TI - The histone deacetylase inhibitor PXD101 increases the efficacy of irinotecan in in vitro and in vivo colon cancer models SN - 1432-0843 PY - 2011///1003 KW - Animals KW - Antineoplastic Agents KW - administration & dosage KW - Antineoplastic Combined Chemotherapy Protocols KW - Apoptosis KW - drug effects KW - Camptothecin KW - Cell Proliferation KW - Colonic Neoplasms KW - drug therapy KW - Drug Synergism KW - Female KW - HCT116 Cells KW - HT29 Cells KW - Histone Deacetylase Inhibitors KW - Humans KW - Hydroxamic Acids KW - Irinotecan KW - Mice KW - Mice, Nude KW - Prodrugs KW - Random Allocation KW - Sulfonamides KW - Topoisomerase I Inhibitors KW - Tumor Burden KW - Whole Body Imaging KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1007/s00280-010-1495-6 ER -