TY  - GEN
AU  - Jin,Yi
AU  - Zollinger,Markus
AU  - Borell,Hubert
AU  - Zimmerlin,Alfred
AU  - Patten,Christopher J
TI  - CYP4F enzymes are responsible for the elimination of fingolimod (FTY720), a novel treatment of relapsing multiple sclerosis
SN  - 1521-009X
PY  - 2011///0428
KW  - Aryl Hydrocarbon Hydroxylases
KW  - genetics
KW  - Biotransformation
KW  - Chromatography, High Pressure Liquid
KW  - Cytochrome P-450 Enzyme System
KW  - Cytochrome P450 Family 4
KW  - Fingolimod Hydrochloride
KW  - Humans
KW  - In Vitro Techniques
KW  - Mass Spectrometry
KW  - Microsomes, Liver
KW  - metabolism
KW  - Molecular Structure
KW  - Multiple Sclerosis, Relapsing-Remitting
KW  - drug therapy
KW  - Oxidation-Reduction
KW  - Propylene Glycols
KW  - chemistry
KW  - Sphingosine
KW  - analogs & derivatives
KW  - Transfection
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1124/dmd.110.035378
ER  -