TY - GEN AU - Yazdi,Amir S AU - Guarda,Greta AU - Riteau,Nicolas AU - Drexler,Stefan K AU - Tardivel,Aubry AU - Couillin,Isabelle AU - Tschopp,Jürg TI - Nanoparticles activate the NLR pyrin domain containing 3 (Nlrp3) inflammasome and cause pulmonary inflammation through release of IL-1α and IL-1β SN - 1091-6490 PY - 2010///1230 KW - Animals KW - Carrier Proteins KW - drug effects KW - Inflammasomes KW - Inhalation KW - Interleukin-1alpha KW - metabolism KW - Interleukin-1beta KW - Keratinocytes KW - Mice KW - NLR Family, Pyrin Domain-Containing 3 Protein KW - Nanoparticles KW - toxicity KW - Pneumonia KW - etiology KW - Receptors, Interleukin-1 KW - Signal Transduction KW - immunology KW - Silicon Dioxide KW - Titanium KW - Zinc Oxide N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1073/pnas.1008155107 ER -