TY  - GEN
AU  - Peirce,Susan K
AU  - Findley,Harry W
AU  - Prince,Chengyu
AU  - Dasgupta,Anindya
AU  - Cooper,Todd
AU  - Durden,Donald L
TI  - The PI-3 kinase-Akt-MDM2-survivin signaling axis in high-risk neuroblastoma: a target for PI-3 kinase inhibitor intervention
SN  - 1432-0843
PY  - 2011///1003
KW  - Animals
KW  - Antineoplastic Agents
KW  - antagonists & inhibitors
KW  - Apoptosis
KW  - drug effects
KW  - Cell Line, Tumor
KW  - Cell Movement
KW  - Cell Proliferation
KW  - Chromones
KW  - Enzyme Inhibitors
KW  - pharmacology
KW  - Female
KW  - Humans
KW  - Inhibitor of Apoptosis Proteins
KW  - metabolism
KW  - Mice
KW  - Mice, Nude
KW  - Neuroblastoma
KW  - drug therapy
KW  - Oligopeptides
KW  - Phosphoinositide-3 Kinase Inhibitors
KW  - Phosphorylation
KW  - Prodrugs
KW  - Protein Processing, Post-Translational
KW  - Proto-Oncogene Proteins c-akt
KW  - Proto-Oncogene Proteins c-mdm2
KW  - Random Allocation
KW  - Signal Transduction
KW  - Survivin
KW  - Tumor Burden
KW  - Xenograft Model Antitumor Assays
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1007/s00280-010-1486-7
ER  -