TY  - GEN
AU  - Wang,Xiaolun
AU  - Berger,Dan M
AU  - Salaski,Edward J
AU  - Torres,Nancy
AU  - Dutia,Minu
AU  - Hanna,Cilien
AU  - Hu,Yongbo
AU  - Levin,Jeremy I
AU  - Powell,Dennis
AU  - Wojciechowicz,Donald
AU  - Collins,Karen
AU  - Frommer,Eileen
AU  - Lucas,Judy
TI  - Indazolylpyrazolopyrimidine as highly potent B-Raf inhibitors with in vivo activity
SN  - 1520-4804
PY  - 2010///1228
KW  - Animals
KW  - Antineoplastic Agents
KW  - chemical synthesis
KW  - Bridged Bicyclo Compounds, Heterocyclic
KW  - Cell Line, Tumor
KW  - Drug Screening Assays, Antitumor
KW  - Humans
KW  - Indazoles
KW  - Mice
KW  - Models, Molecular
KW  - Mutation
KW  - Neoplasm Transplantation
KW  - Proto-Oncogene Proteins B-raf
KW  - antagonists & inhibitors
KW  - Pyrazoles
KW  - Pyrimidines
KW  - Structure-Activity Relationship
KW  - Transplantation, Heterologous
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1021/jm1007566
ER  -