TY  - GEN
AU  - Vidarsdottir,Linda
AU  - Steingrimsdottir,Gudridur
AU  - Bodvarsdottir,Sigridur Klara
AU  - Ogmundsdottir,Helga Margret
AU  - Eyfjord,Jorunn Erla
TI  - Sensitivity of BRCA2 mutated human cell lines to Aurora kinase inhibition
SN  - 1573-0646
PY  - 2012///0611
KW  - Antineoplastic Agents
KW  - pharmacology
KW  - Aurora Kinases
KW  - BRCA2 Protein
KW  - genetics
KW  - Benzamides
KW  - Breast Neoplasms
KW  - enzymology
KW  - Cell Death
KW  - drug effects
KW  - Cell Line, Tumor
KW  - Cell Size
KW  - Cell Survival
KW  - Cytokinesis
KW  - Dose-Response Relationship, Drug
KW  - Female
KW  - Humans
KW  - Inhibitory Concentration 50
KW  - Mitosis
KW  - Molecular Targeted Therapy
KW  - Mutation
KW  - Pancreatic Neoplasms
KW  - Ploidies
KW  - Protein Kinase Inhibitors
KW  - Protein Serine-Threonine Kinases
KW  - antagonists & inhibitors
KW  - Quinazolines
KW  - RNA, Messenger
KW  - metabolism
KW  - Transfection
KW  - Tumor Suppressor Protein p53
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1007/s10637-010-9566-4
ER  -