TY - GEN AU - Ryan,Sinéad M AU - Frías,Jesús M AU - Wang,Xuexuan AU - Sayers,Claire T AU - Haddleton,David M AU - Brayden,David J TI - PK/PD modelling of comb-shaped PEGylated salmon calcitonin conjugates of differing molecular weights SN - 1873-4995 PY - 2011///0512 KW - Animals KW - Binding Sites KW - Bone Density Conservation Agents KW - administration & dosage KW - Calcitonin KW - Calcium KW - blood KW - Cell Line, Tumor KW - Chromatography, High Pressure Liquid KW - Cyclic AMP KW - metabolism KW - Drug Carriers KW - chemistry KW - Drug Stability KW - Humans KW - Injections, Intraperitoneal KW - Intestines KW - enzymology KW - Liver KW - Male KW - Methacrylates KW - Models, Biological KW - Molecular Weight KW - Polyethylene Glycols KW - Polymethacrylic Acids KW - Rats KW - Rats, Wistar KW - Substrate Specificity N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.jconrel.2010.10.004 ER -