TY  - GEN
AU  - Sun,Lingzhi
AU  - Shah,Falgun
AU  - Helal,Mohamed A
AU  - Wu,Yunshan
AU  - Pedduri,Yakambram
AU  - Chittiboyina,Amar G
AU  - Gut,Jiri
AU  - Rosenthal,Philip J
AU  - Avery,Mitchell A
TI  - Design, synthesis, and development of novel guaianolide-endoperoxides as potential antimalarial agents
SN  - 1520-4804
PY  - 2010///1228
KW  - Animals
KW  - Antimalarials
KW  - chemical synthesis
KW  - Artemisinins
KW  - pharmacology
KW  - Chlorocebus aethiops
KW  - Drug Design
KW  - Hydrophobic and Hydrophilic Interactions
KW  - Models, Molecular
KW  - Parasitic Sensitivity Tests
KW  - Peroxides
KW  - Plasmodium falciparum
KW  - drug effects
KW  - Sarcoplasmic Reticulum Calcium-Transporting ATPases
KW  - chemistry
KW  - Sesquiterpenes, Guaiane
KW  - Stereoisomerism
KW  - Structure-Activity Relationship
KW  - Thapsigargin
KW  - Vero Cells
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1021/jm1006462
ER  -