TY - GEN AU - Hotz,Birgit AU - Backer,Marina V AU - Backer,Joseph M AU - Buhr,Heinz-J AU - Hotz,Hubert G TI - Specific targeting of tumor endothelial cells by a shiga-like toxin-vascular endothelial growth factor fusion protein as a novel treatment strategy for pancreatic cancer SN - 1476-5586 PY - 2011///0203 KW - Adenocarcinoma KW - metabolism KW - Animals KW - Antimetabolites, Antineoplastic KW - therapeutic use KW - Blotting, Western KW - Cell Movement KW - Cell Proliferation KW - Cells, Cultured KW - Combined Modality Therapy KW - Deoxycytidine KW - analogs & derivatives KW - Disease Models, Animal KW - Endothelium, Vascular KW - cytology KW - Humans KW - Immunoenzyme Techniques KW - Male KW - Mice KW - Mice, Nude KW - Neoplasm Metastasis KW - Neovascularization, Pathologic KW - prevention & control KW - Pancreatic Neoplasms KW - RNA, Messenger KW - genetics KW - Recombinant Fusion Proteins KW - Reverse Transcriptase Polymerase Chain Reaction KW - Shiga Toxins KW - Signal Transduction KW - Survival Rate KW - Vascular Endothelial Growth Factor A KW - Vascular Endothelial Growth Factor Receptor-2 KW - antagonists & inhibitors KW - Xenograft Model Antitumor Assays KW - Gemcitabine N1 - Publication Type: Comparative Study; Journal Article UR - https://doi.org/10.1593/neo.10418 ER -