TY - GEN AU - Lau,Wai Leung AU - Degrado,William F AU - Roder,Heinrich TI - The effects of pK(a) tuning on the thermodynamics and kinetics of folding: design of a solvent-shielded carboxylate pair at the a-position of a coiled-coil SN - 1542-0086 PY - 2011///0120 KW - Basic-Leucine Zipper Transcription Factors KW - chemistry KW - Carboxylic Acids KW - Circular Dichroism KW - Hydrogen-Ion Concentration KW - Kinetics KW - Protein Denaturation KW - Protein Folding KW - Protein Multimerization KW - Protein Stability KW - Protein Structure, Secondary KW - Saccharomyces cerevisiae Proteins KW - Solvents KW - Thermodynamics N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural UR - https://doi.org/10.1016/j.bpj.2010.07.059 ER -