Characterization of Puma-dependent and Puma-independent neuronal cell death pathways following prolonged proteasomal inhibition. [electronic resource]
- Molecular and cellular biology Dec 2010
- 5484-501 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1098-5549
10.1128/MCB.00575-10 doi
Animals Apoptosis--drug effects Apoptosis Regulatory Proteins--deficiency Autophagy BH3 Interacting Domain Death Agonist Protein--deficiency Base Sequence Bcl-2-Like Protein 11 Caspase 3--metabolism Cathepsins--metabolism Cytochromes c--metabolism DNA Primers--genetics Fluorescence Resonance Energy Transfer Gene Expression Lysosomes--drug effects Membrane Potential, Mitochondrial Membrane Proteins--deficiency Mice Mice, Inbred C57BL Mice, Knockout Models, Neurological Nerve Degeneration--genetics Neurons--cytology Protease Inhibitors--pharmacology Proteasome Inhibitors Proto-Oncogene Proteins--deficiency Proto-Oncogene Proteins c-bcl-2--genetics RNA, Small Interfering--genetics Stress, Physiological Tumor Suppressor Proteins--deficiency