TY - GEN AU - Richter,Nina AU - Breicha,Klaus AU - Hummel,Werner AU - Niefind,Karsten TI - The three-dimensional structure of AKR11B4, a glycerol dehydrogenase from Gluconobacter oxydans, reveals a tryptophan residue as an accelerator of reaction turnover SN - 1089-8638 PY - 2010///1216 KW - Amino Acid Sequence KW - Amino Acid Substitution KW - Apraxia, Ideomotor KW - Bacterial Proteins KW - chemistry KW - Catalytic Domain KW - genetics KW - Crystallography, X-Ray KW - Gluconobacter oxydans KW - enzymology KW - Hydrophobic and Hydrophilic Interactions KW - Models, Molecular KW - Molecular Sequence Data KW - Mutagenesis, Site-Directed KW - NADP KW - metabolism KW - Protein Conformation KW - Recombinant Proteins KW - Sequence Homology, Amino Acid KW - Static Electricity KW - Structural Homology, Protein KW - Substrate Specificity KW - Sugar Alcohol Dehydrogenases KW - Tryptophan N1 - Publication Type: Journal Article UR - https://doi.org/10.1016/j.jmb.2010.09.049 ER -