Provencher-Mandeville, Josée

Design, synthesis and biological evaluation of estradiol-PEG-linked platinum(II) hybrid molecules: comparative molecular modeling study of three distinct families of hybrids. [electronic resource] - Steroids Jan 2011 - 94-103 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

1878-5867

10.1016/j.steroids.2010.09.004 doi


Antineoplastic Agents--chemical synthesis
Binding Sites--drug effects
Cell Line, Tumor
Cell Proliferation--drug effects
Dose-Response Relationship, Drug
Drug Screening Assays, Antitumor
Estradiol--chemistry
Estrogen Receptor alpha--chemistry
Humans
Models, Molecular
Molecular Conformation
Organometallic Compounds--chemical synthesis
Platinum--chemistry
Polyethylene Glycols--chemistry
Stereoisomerism