TY - GEN AU - Chutinimitkul,Salin AU - Herfst,Sander AU - Steel,John AU - Lowen,Anice C AU - Ye,Jianqiang AU - van Riel,Debby AU - Schrauwen,Eefje J A AU - Bestebroer,Theo M AU - Koel,Björn AU - Burke,David F AU - Sutherland-Cash,Kyle H AU - Whittleston,Chris S AU - Russell,Colin A AU - Wales,David J AU - Smith,Derek J AU - Jonges,Marcel AU - Meijer,Adam AU - Koopmans,Marion AU - Rimmelzwaan,Guus F AU - Kuiken,Thijs AU - Osterhaus,Albert D M E AU - García-Sastre,Adolfo AU - Perez,Daniel R AU - Fouchier,Ron A M TI - Virulence-associated substitution D222G in the hemagglutinin of 2009 pandemic influenza A(H1N1) virus affects receptor binding SN - 1098-5514 PY - 2010///1122 KW - Amino Acid Motifs KW - Amino Acid Substitution KW - Animals KW - Binding Sites KW - Cell Line KW - Disease Models, Animal KW - Dogs KW - Female KW - Ferrets KW - Guinea Pigs KW - Hemagglutinin Glycoproteins, Influenza Virus KW - chemistry KW - Humans KW - Influenza A Virus, H1N1 Subtype KW - genetics KW - Influenza, Human KW - epidemiology KW - Male KW - Mice KW - Mice, Inbred BALB C KW - Models, Molecular KW - N-Acetylneuraminic Acid KW - Pandemics KW - Receptors, Virus KW - Turkeys KW - Virulence KW - Virus Attachment N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1128/JVI.01136-10 ER -