TY  - GEN
AU  - Kidera,Yasuhiro
AU  - Tsubaki,Masanobu
AU  - Yamazoe,Yuzuru
AU  - Shoji,Kaori
AU  - Nakamura,Haruyuki
AU  - Ogaki,Mitsuhiko
AU  - Satou,Takao
AU  - Itoh,Tatsuki
AU  - Isozaki,Misako
AU  - Kaneko,Junichi
AU  - Tanimori,Yoshihiro
AU  - Yanae,Masashi
AU  - Nishida,Shozo
TI  - Reduction of lung metastasis, cell invasion, and adhesion in mouse melanoma by statin-induced blockade of the Rho/Rho-associated coiled-coil-containing protein kinase pathway
SN  - 1756-9966
PY  - 2010///1228
KW  - Administration, Oral
KW  - Animals
KW  - Antineoplastic Agents
KW  - administration & dosage
KW  - Blotting, Western
KW  - Cell Adhesion
KW  - drug effects
KW  - Cell Movement
KW  - Cell Survival
KW  - Extracellular Matrix Proteins
KW  - metabolism
KW  - Fatty Acids, Monounsaturated
KW  - pharmacology
KW  - Female
KW  - Fluvastatin
KW  - Gene Expression Regulation, Enzymologic
KW  - Gene Expression Regulation, Neoplastic
KW  - Hydroxymethylglutaryl-CoA Reductase Inhibitors
KW  - Indoles
KW  - Integrins
KW  - Lim Kinases
KW  - Lung Neoplasms
KW  - enzymology
KW  - Matrix Metalloproteinases
KW  - genetics
KW  - Melanoma, Experimental
KW  - drug therapy
KW  - Mice
KW  - Mice, Inbred C57BL
KW  - Myosin Light Chains
KW  - Neoplasm Invasiveness
KW  - Phosphorylation
KW  - Protein Kinase Inhibitors
KW  - RNA, Messenger
KW  - Reverse Transcriptase Polymerase Chain Reaction
KW  - Signal Transduction
KW  - Simvastatin
KW  - Time Factors
KW  - rho GTP-Binding Proteins
KW  - rho-Associated Kinases
KW  - antagonists & inhibitors
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1186/1756-9966-29-127
ER  -