Lin, Hui-Hsuan

Protocatechuic acid inhibits cancer cell metastasis involving the down-regulation of Ras/Akt/NF-κB pathway and MMP-2 production by targeting RhoB activation. [electronic resource] - British journal of pharmacology Jan 2011 - 237-54 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1476-5381

10.1111/j.1476-5381.2010.01022.x doi


Animals
Anticarcinogenic Agents--pharmacology
Blotting, Western
Down-Regulation--drug effects
Electrophoretic Mobility Shift Assay
Hydroxybenzoates--pharmacology
Immunoprecipitation
Matrix Metalloproteinase 2--biosynthesis
Melanoma, Experimental--enzymology
Mice
NF-kappa B--metabolism
Neoplasm Metastasis--prevention & control
Proto-Oncogene Proteins c-akt--metabolism
Reverse Transcriptase Polymerase Chain Reaction
ras Proteins--metabolism
rhoB GTP-Binding Protein--metabolism