TY  - GEN
AU  - Howell,Owain W
AU  - Rundle,Jon L
AU  - Garg,Anurag
AU  - Komada,Masayuki
AU  - Brophy,Peter J
AU  - Reynolds,Richard
TI  - Activated microglia mediate axoglial disruption that contributes to axonal injury in multiple sclerosis
SN  - 1554-6578
PY  - 2010///1015
KW  - Adult
KW  - Aged
KW  - Analysis of Variance
KW  - Animals
KW  - Anti-Bacterial Agents
KW  - pharmacology
KW  - Axons
KW  - pathology
KW  - Brain
KW  - metabolism
KW  - CD3 Complex
KW  - Calcium-Binding Proteins
KW  - Caspase 1
KW  - DNA-Binding Proteins
KW  - Encephalomyelitis, Autoimmune, Experimental
KW  - chemically induced
KW  - Female
KW  - Gene Expression Regulation
KW  - drug effects
KW  - Glycoproteins
KW  - HLA-DR Antigens
KW  - Humans
KW  - Indoles
KW  - Kv1.2 Potassium Channel
KW  - Male
KW  - Mice
KW  - Mice, Inbred C57BL
KW  - Microfilament Proteins
KW  - Microglia
KW  - immunology
KW  - Microscopy, Confocal
KW  - Middle Aged
KW  - Minocycline
KW  - Multiple Sclerosis
KW  - Myelin-Oligodendrocyte Glycoprotein
KW  - NAV1.6 Voltage-Gated Sodium Channel
KW  - Nerve Tissue Proteins
KW  - Neurofilament Proteins
KW  - Nitric Oxide Synthase Type II
KW  - Peptide Fragments
KW  - Postmortem Changes
KW  - Ranvier's Nodes
KW  - Sodium Channels
KW  - Toll-Like Receptor 4
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1097/NEN.0b013e3181f3a5b1
ER  -