Simoni, Elena

Polyamine conjugation of curcumin analogues toward the discovery of mitochondria-directed neuroprotective agents. [electronic resource] - Journal of medicinal chemistry Oct 2010 - 7264-8 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1520-4804

10.1021/jm100637k doi


Animals
Antineoplastic Agents--chemical synthesis
Antioxidants--chemical synthesis
Cattle
Cell Line
Cell Line, Tumor
Cell Proliferation--drug effects
Curcumin--analogs & derivatives
Drug Screening Assays, Antitumor
Endothelial Cells--drug effects
Endothelium, Vascular--drug effects
Enzyme Activation
Fibroblasts--cytology
Heme Oxygenase-1--metabolism
Humans
In Vitro Techniques
Mice
Mitochondria--drug effects
Neuroprotective Agents--chemical synthesis
Oxidative Stress--drug effects
Polyamines--chemical synthesis
Reactive Oxygen Species--metabolism
Stereoisomerism
Structure-Activity Relationship