TY - GEN AU - Lacher,M D AU - Pincheira,R AU - Zhu,Z AU - Camoretti-Mercado,B AU - Matli,M AU - Warren,R S AU - Castro,A F TI - Rheb activates AMPK and reduces p27Kip1 levels in Tsc2-null cells via mTORC1-independent mechanisms: implications for cell proliferation and tumorigenesis SN - 1476-5594 PY - 2011///0111 KW - AMP-Activated Protein Kinases KW - metabolism KW - Animals KW - Cell Line, Tumor KW - Cell Proliferation KW - Cell Transformation, Neoplastic KW - Colonic Neoplasms KW - Cyclin-Dependent Kinase 2 KW - analysis KW - Cyclin-Dependent Kinase Inhibitor p27 KW - Female KW - Humans KW - Mechanistic Target of Rapamycin Complex 1 KW - Mice KW - Mice, Nude KW - Monomeric GTP-Binding Proteins KW - Multiprotein Complexes KW - Neuropeptides KW - Proteins KW - Ras Homolog Enriched in Brain Protein KW - TOR Serine-Threonine Kinases KW - Tuberous Sclerosis Complex 2 Protein KW - Tumor Suppressor Proteins KW - Up-Regulation N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S UR - https://doi.org/10.1038/onc.2010.393 ER -