Lacher, M D <br/><br/>
Rheb activates AMPK and reduces p27Kip1 levels in Tsc2-null cells via mTORC1-independent mechanisms: implications for cell proliferation and tumorigenesis.  [electronic resource] 

 -  Oncogene  Dec 2010 
 - 6543-56 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. 
<br/><br/><label>ISSN: </label>1476-5594 
<br/><br/><label>Standard No.: </label>10.1038/onc.2010.393  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>AMP-Activated Protein Kinases--metabolism<br/>Animals<br/>Cell Line, Tumor<br/>Cell Proliferation<br/>Cell Transformation, Neoplastic--metabolism<br/>Colonic Neoplasms--metabolism<br/>Cyclin-Dependent Kinase 2--analysis<br/>Cyclin-Dependent Kinase Inhibitor p27--analysis<br/>Female<br/>Humans<br/>Mechanistic Target of Rapamycin Complex 1<br/>Mice<br/>Mice, Nude<br/>Monomeric GTP-Binding Proteins--metabolism<br/>Multiprotein Complexes<br/>Neuropeptides--metabolism<br/>Proteins--metabolism<br/>Ras Homolog Enriched in Brain Protein<br/>TOR Serine-Threonine Kinases<br/>Tuberous Sclerosis Complex 2 Protein<br/>Tumor Suppressor Proteins--analysis<br/>Up-Regulation