TY  - GEN
AU  - Rottmann,Matthias
AU  - McNamara,Case
AU  - Yeung,Bryan K S
AU  - Lee,Marcus C S
AU  - Zou,Bin
AU  - Russell,Bruce
AU  - Seitz,Patrick
AU  - Plouffe,David M
AU  - Dharia,Neekesh V
AU  - Tan,Jocelyn
AU  - Cohen,Steven B
AU  - Spencer,Kathryn R
AU  - González-Páez,Gonzalo E
AU  - Lakshminarayana,Suresh B
AU  - Goh,Anne
AU  - Suwanarusk,Rossarin
AU  - Jegla,Timothy
AU  - Schmitt,Esther K
AU  - Beck,Hans-Peter
AU  - Brun,Reto
AU  - Nosten,Francois
AU  - Renia,Laurent
AU  - Dartois,Veronique
AU  - Keller,Thomas H
AU  - Fidock,David A
AU  - Winzeler,Elizabeth A
AU  - Diagana,Thierry T
TI  - Spiroindolones, a potent compound class for the treatment of malaria
SN  - 1095-9203
PY  - 2010///0927
KW  - Adenosine Triphosphatases
KW  - antagonists & inhibitors
KW  - Animals
KW  - Antimalarials
KW  - administration & dosage
KW  - Cell Line
KW  - Drug Discovery
KW  - Drug Resistance
KW  - Erythrocytes
KW  - parasitology
KW  - Female
KW  - Genes, Protozoan
KW  - Humans
KW  - Indoles
KW  - Malaria
KW  - drug therapy
KW  - Male
KW  - Mice
KW  - Models, Molecular
KW  - Mutant Proteins
KW  - Mutation
KW  - Parasitic Sensitivity Tests
KW  - Plasmodium berghei
KW  - drug effects
KW  - Plasmodium falciparum
KW  - Plasmodium vivax
KW  - Protein Synthesis Inhibitors
KW  - Protozoan Proteins
KW  - biosynthesis
KW  - Rats
KW  - Rats, Wistar
KW  - Spiro Compounds
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1126/science.1193225
ER  -