TY - GEN AU - Abusnina,Abdurazzag AU - Alhosin,Mahmoud AU - Keravis,Thérèse AU - Muller,Christian D AU - Fuhrmann,Guy AU - Bronner,Christian AU - Lugnier,Claire TI - Down-regulation of cyclic nucleotide phosphodiesterase PDE1A is the key event of p73 and UHRF1 deregulation in thymoquinone-induced acute lymphoblastic leukemia cell apoptosis SN - 1873-3913 PY - 2011///0208 KW - Antineoplastic Agents KW - pharmacology KW - Apoptosis KW - Benzoquinones KW - CCAAT-Enhancer-Binding Proteins KW - metabolism KW - Cell Cycle Proteins KW - Cell Line KW - Cyclic Nucleotide Phosphodiesterases, Type 1 KW - antagonists & inhibitors KW - DNA-Binding Proteins KW - Down-Regulation KW - Humans KW - Isoenzymes KW - genetics KW - Jurkat Cells KW - Nuclear Proteins KW - Precursor Cell Lymphoblastic Leukemia-Lymphoma KW - enzymology KW - RNA Interference KW - Tumor Protein p73 KW - Tumor Suppressor Proteins KW - Ubiquitin-Protein Ligases N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.cellsig.2010.08.015 ER -