Becker, Richard C

Effect of apixaban, an oral and direct factor Xa inhibitor, on coagulation activity biomarkers following acute coronary syndrome. [electronic resource] - Thrombosis and haemostasis Nov 2010 - 976-83 p. digital

Publication Type: Clinical Trial, Phase II; Journal Article; Multicenter Study; Randomized Controlled Trial

2567-689X

10.1160/TH10-04-0247 doi


Acute Coronary Syndrome--blood
Administration, Oral
Adult
Aged
Aged, 80 and over
Biomarkers--blood
Blood Coagulation--drug effects
Chi-Square Distribution
Chromatography, Liquid
Dose-Response Relationship, Drug
Double-Blind Method
Down-Regulation
Enzyme-Linked Immunosorbent Assay
Factor Xa--metabolism
Factor Xa Inhibitors
Female
Fibrin Fibrinogen Degradation Products--metabolism
Fibrinolytic Agents--administration & dosage
Humans
International Normalized Ratio
Male
Middle Aged
Odds Ratio
Partial Thromboplastin Time
Peptide Fragments--blood
Placebo Effect
Prothrombin
Pyrazoles--administration & dosage
Pyridones--administration & dosage
Tandem Mass Spectrometry
Thrombin--metabolism
Time Factors
Treatment Outcome