Becker, Richard C
Effect of apixaban, an oral and direct factor Xa inhibitor, on coagulation activity biomarkers following acute coronary syndrome. [electronic resource]
- Thrombosis and haemostasis Nov 2010
- 976-83 p. digital
Publication Type: Clinical Trial, Phase II; Journal Article; Multicenter Study; Randomized Controlled Trial
ISSN: 2567-689X
Standard No.: 10.1160/TH10-04-0247 doi
Subjects--Topical Terms: Acute Coronary Syndrome--blood Administration, Oral Adult Aged Aged, 80 and over Biomarkers--blood Blood Coagulation--drug effects Chi-Square Distribution Chromatography, Liquid Dose-Response Relationship, Drug Double-Blind Method Down-Regulation Enzyme-Linked Immunosorbent Assay Factor Xa--metabolism Factor Xa Inhibitors Female Fibrin Fibrinogen Degradation Products--metabolism Fibrinolytic Agents--administration & dosage Humans International Normalized Ratio Male Middle Aged Odds Ratio Partial Thromboplastin Time Peptide Fragments--blood Placebo Effect Prothrombin Pyrazoles--administration & dosage Pyridones--administration & dosage Tandem Mass Spectrometry Thrombin--metabolism Time Factors Treatment Outcome