TY - GEN AU - Tao,Zhihua AU - Barker,John AU - Shi,Stone D-H AU - Gehring,Michael AU - Sun,Shaoxian TI - Steady-state kinetic and inhibition studies of the mammalian target of rapamycin (mTOR) kinase domain and mTOR complexes SN - 1520-4995 PY - 2011///0125 KW - Adaptor Proteins, Signal Transducing KW - antagonists & inhibitors KW - Amino Acid Sequence KW - Carrier Proteins KW - Cell Line KW - Enzyme Inhibitors KW - pharmacology KW - Humans KW - Intracellular Signaling Peptides and Proteins KW - Kinetics KW - Mechanistic Target of Rapamycin Complex 1 KW - Metals KW - metabolism KW - Molecular Sequence Data KW - Multiprotein Complexes KW - Phosphorylation KW - Proteins KW - Rapamycin-Insensitive Companion of mTOR Protein KW - Recombinant Proteins KW - Regulatory-Associated Protein of mTOR KW - Sirolimus KW - Substrate Specificity KW - TOR Serine-Threonine Kinases KW - Up-Regulation KW - mTOR Associated Protein, LST8 Homolog N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1021/bi100673c ER -