Steady-state kinetic and inhibition studies of the mammalian target of rapamycin (mTOR) kinase domain and mTOR complexes. [electronic resource]
- Biochemistry Oct 2010
- 8488-98 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1520-4995
10.1021/bi100673c doi
Adaptor Proteins, Signal Transducing--antagonists & inhibitors Amino Acid Sequence Carrier Proteins--antagonists & inhibitors Cell Line Enzyme Inhibitors--pharmacology Humans Intracellular Signaling Peptides and Proteins Kinetics Mechanistic Target of Rapamycin Complex 1 Metals--metabolism Molecular Sequence Data Multiprotein Complexes Phosphorylation Proteins--antagonists & inhibitors Rapamycin-Insensitive Companion of mTOR Protein Recombinant Proteins--antagonists & inhibitors Regulatory-Associated Protein of mTOR Sirolimus--pharmacology Substrate Specificity TOR Serine-Threonine Kinases--antagonists & inhibitors Up-Regulation mTOR Associated Protein, LST8 Homolog