TY - GEN AU - McCloskey,D E AU - McGuire,J J AU - Russell,C A AU - Rowan,B G AU - Bertino,J R AU - Pizzorno,G AU - Mini,E TI - Decreased folylpolyglutamate synthetase activity as a mechanism of methotrexate resistance in CCRF-CEM human leukemia sublines SN - 0021-9258 PY - 1991///0501 KW - Drug Resistance KW - Humans KW - Leukemia KW - enzymology KW - Methotrexate KW - metabolism KW - Peptide Synthases KW - Phenotype KW - Thymidylate Synthase KW - Tumor Cells, Cultured N1 - Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S ER -