Ji, C <br/><br/>
Exogenous cell-permeable C6 ceramide sensitizes multiple cancer cell lines to Doxorubicin-induced apoptosis by promoting AMPK activation and mTORC1 inhibition.  [electronic resource] 

 -  Oncogene  Dec 2010 
 - 6557-68 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1476-5594 
<br/><br/><label>Standard No.: </label>10.1038/onc.2010.379  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>AMP-Activated Protein Kinases--metabolism<br/>Aminoimidazole Carboxamide--analogs & derivatives<br/>Antineoplastic Agents--therapeutic use<br/>Antineoplastic Combined Chemotherapy Protocols<br/>Apoptosis--drug effects<br/>Cell Line, Tumor<br/>Ceramides--pharmacology<br/>Doxorubicin--therapeutic use<br/>Drug Resistance, Neoplasm--drug effects<br/>Humans<br/>Mechanistic Target of Rapamycin Complex 1<br/>Multiprotein Complexes<br/>Neoplasms--drug therapy<br/>Proteins--antagonists & inhibitors<br/>Reactive Oxygen Species--metabolism<br/>Ribonucleotides--pharmacology<br/>TOR Serine-Threonine Kinases