TY - GEN AU - Salvati,E AU - Scarsella,M AU - Porru,M AU - Rizzo,A AU - Iachettini,S AU - Tentori,L AU - Graziani,G AU - D'Incalci,M AU - Stevens,M F G AU - Orlandi,A AU - Passeri,D AU - Gilson,E AU - Zupi,G AU - Leonetti,C AU - Biroccio,A TI - PARP1 is activated at telomeres upon G4 stabilization: possible target for telomere-based therapy SN - 1476-5594 PY - 2010///1228 KW - Acridines KW - metabolism KW - Animals KW - Antineoplastic Agents KW - DNA Damage KW - DNA Repair KW - drug effects KW - Drug Synergism KW - Enzyme Activation KW - Enzyme Inhibitors KW - pharmacology KW - G-Quadruplexes KW - HCT116 Cells KW - HT29 Cells KW - Humans KW - Male KW - Mice KW - Poly(ADP-ribose) Polymerases KW - Protein Transport KW - Telomere KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/onc.2010.344 ER -