TY  - GEN
AU  - Zhang,Xiaoyu
AU  - Zhao,Xiaofeng
AU  - Ma,Zhongjun
TI  - PYDDT, a novel phase 2 enzymes inducer, activates Keap1-Nrf2 pathway via depleting the cellular level of glutathione
SN  - 1879-3169
PY  - 2010///1020
KW  - Adaptor Proteins, Signal Transducing
KW  - biosynthesis
KW  - Animals
KW  - Cell Line, Tumor
KW  - Cell Survival
KW  - Cytoskeletal Proteins
KW  - Drugs, Chinese Herbal
KW  - chemistry
KW  - Enzyme Induction
KW  - Glutathione
KW  - metabolism
KW  - Hepatocytes
KW  - drug effects
KW  - Kelch-Like ECH-Associated Protein 1
KW  - Metabolic Detoxication, Phase II
KW  - Mice
KW  - NF-E2-Related Factor 2
KW  - Oxidative Stress
KW  - Plant Extracts
KW  - pharmacology
KW  - Plants, Medicinal
KW  - Protein Processing, Post-Translational
KW  - Reactive Oxygen Species
KW  - Signal Transduction
KW  - Thiophenes
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/j.toxlet.2010.08.011
ER  -