Development and application of an LC-MS/MS method for the detection of the vinyl chloride-induced DNA adduct N(2),3-ethenoguanine in tissues of adult and weanling rats following exposure to [(13)C(2)]-VC. [electronic resource]
- Chemical research in toxicology Sep 2010
- 1485-91 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural
1520-5010
10.1021/tx1001767 doi
Animals Carbon Isotopes--chemistry Carcinogens--chemistry Chromatography, High Pressure Liquid--methods DNA Adducts--analysis Guanine--analogs & derivatives Half-Life Kidney--drug effects Liver--drug effects Lung--drug effects Male Rats Rats, Sprague-Dawley Tandem Mass Spectrometry--methods Vinyl Chloride--chemistry