TY  - GEN
AU  - Mabondzo,Aloïse
AU  - Bottlaender,Michel
AU  - Guyot,Anne-Cécile
AU  - Tsaouin,Katya
AU  - Deverre,Jean Robert
AU  - Balimane,Praveen V
TI  - Validation of in vitro cell-based human blood-brain barrier model using clinical positron emission tomography radioligands to predict in vivo human brain penetration
SN  - 1543-8392
PY  - 2013///0529
KW  - ATP-Binding Cassette Transporters
KW  - genetics
KW  - Blood-Brain Barrier
KW  - physiology
KW  - Brain
KW  - diagnostic imaging
KW  - Caco-2 Cells
KW  - Claudins
KW  - Drug Discovery
KW  - Humans
KW  - Kinetics
KW  - Models, Neurological
KW  - Permeability
KW  - Positron-Emission Tomography
KW  - RNA, Messenger
KW  - Radiopharmaceuticals
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Validation Study
UR  - https://doi.org/10.1021/mp1002366
ER  -