TY - GEN AU - Crowley,Emily AU - O'Mara,Megan L AU - Kerr,Ian D AU - Callaghan,Richard TI - Transmembrane helix 12 plays a pivotal role in coupling energy provision and drug binding in ABCB1 SN - 1742-4658 PY - 2010///1027 KW - ATP Binding Cassette Transporter, Subfamily B KW - chemistry KW - ATP Binding Cassette Transporter, Subfamily B, Member 1 KW - Animals KW - Binding Sites KW - Catalytic Domain KW - Cysteine KW - Energy Metabolism KW - Humans KW - Kinetics KW - Models, Molecular KW - Multidrug Resistance-Associated Proteins KW - Mutation KW - Protein Conformation KW - Protein Isoforms KW - metabolism N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1111/j.1742-4658.2010.07789.x ER -