TY  - GEN
AU  - Eich,Marcus
AU  - Roos,Wynand P
AU  - Dianov,Grigory L
AU  - Digweed,Martin
AU  - Kaina,Bernd
TI  - Nijmegen breakage syndrome protein (NBN) causes resistance to methylating anticancer drugs such as temozolomide
SN  - 1521-0111
PY  - 2010///1207
KW  - Antineoplastic Agents, Alkylating
KW  - pharmacology
KW  - Apoptosis
KW  - Caspase 7
KW  - metabolism
KW  - Cell Cycle Proteins
KW  - genetics
KW  - Cell Line, Transformed
KW  - Cell Line, Tumor
KW  - DNA Methylation
KW  - Dacarbazine
KW  - analogs & derivatives
KW  - Drug Resistance, Neoplasm
KW  - Fibroblasts
KW  - drug effects
KW  - Guanine
KW  - Homozygote
KW  - Humans
KW  - Melanoma
KW  - Methylnitronitrosoguanidine
KW  - Mutagens
KW  - Mutation
KW  - Necrosis
KW  - Nijmegen Breakage Syndrome
KW  - pathology
KW  - Nuclear Proteins
KW  - Poly (ADP-Ribose) Polymerase-1
KW  - Poly(ADP-ribose) Polymerases
KW  - Temozolomide
KW  - Uveal Neoplasms
KW  - Uveal Melanoma
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1124/mol.110.066076
ER  -