Eich, Marcus

Nijmegen breakage syndrome protein (NBN) causes resistance to methylating anticancer drugs such as temozolomide. [electronic resource] - Molecular pharmacology Nov 2010 - 943-51 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1521-0111

10.1124/mol.110.066076 doi


Antineoplastic Agents, Alkylating--pharmacology
Apoptosis
Caspase 7--metabolism
Cell Cycle Proteins--genetics
Cell Line, Transformed
Cell Line, Tumor
DNA Methylation
Dacarbazine--analogs & derivatives
Drug Resistance, Neoplasm
Fibroblasts--drug effects
Guanine--analogs & derivatives
Homozygote
Humans
Melanoma
Methylnitronitrosoguanidine--pharmacology
Mutagens--pharmacology
Mutation
Necrosis
Nijmegen Breakage Syndrome--pathology
Nuclear Proteins--genetics
Poly (ADP-Ribose) Polymerase-1
Poly(ADP-ribose) Polymerases--metabolism
Temozolomide
Uveal Neoplasms
Uveal Melanoma