Chowdhury, Morshed A <br/><br/>
Synthesis and biological evaluation of indomethacin analogs possessing a N-difluoromethyl-1,2-dihydropyrid-2-one ring system: a search for novel cyclooxygenase and lipoxygenase inhibitors.  [electronic resource] 

 -  Bioorganic & medicinal chemistry letters  Oct 2010 
 - 5776-80 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1464-3405 
<br/><br/><label>Standard No.: </label>10.1016/j.bmcl.2010.07.132  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Anti-Inflammatory Agents--chemical synthesis<br/>Arachidonate 5-Lipoxygenase--chemistry<br/>Cyclooxygenase 2--chemistry<br/>Cyclooxygenase 2 Inhibitors--chemical synthesis<br/>Edema--chemically induced<br/>Indoles--chemical synthesis<br/>Indomethacin--chemical synthesis<br/>Lipoxygenase Inhibitors--chemical synthesis<br/>Pyridones--chemical synthesis<br/>Rats<br/>Structure-Activity Relationship