Murray, Christopher W <br/><br/>
Fragment-based drug discovery applied to Hsp90. Discovery of two lead series with high ligand efficiency.  [electronic resource] 

 -  Journal of medicinal chemistry  Aug 2010 
 - 5942-55 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1520-4804 
<br/><br/><label>Standard No.: </label>10.1021/jm100059d  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Aminopyridines--chemical synthesis<br/>Antineoplastic Agents--chemistry<br/>Crystallography, X-Ray<br/>Databases, Factual<br/>Drug Design<br/>HSP90 Heat-Shock Proteins--antagonists & inhibitors<br/>Ligands<br/>Magnetic Resonance Spectroscopy<br/>Models, Molecular<br/>Phenols--chemical synthesis<br/>Protein Binding<br/>Protein Structure, Tertiary<br/>Resorcinols--chemical synthesis<br/>Structure-Activity Relationship